";s:4:"text";s:25821:"I am a new dog owner, gave my 14 weeks old german shepherd the 1st Simparica trio pill yesterday morning 8 am, she starts to vomit around 5 pm, having more frequent uranating, and loose poop, this continued until 8 pm when she's tired and finally slept. It works by creating uncontrolled neuromuscular activity leading to death in fleas as well as some ticks and mites. its been 2 weeks .We just had a blood draw done again and they are still high. Being in CT where Lyme disease is high it's a relief to have top shelf protection. Hope your pup is doing better!! The excerpts below from the manufacturers' Prescribing . It has been one week and she has been acting very anxious since. Im wondering if there is any correlation as we havent changed anything else with him. Nobody knows what causes it or makes one dog recover and another not. After reading all these reports I am convinced this is the reason our baby is so sick. Got home 4 hours later and my dog fell down three times and is now seizing mainly her head . The main side effect of Simparica Trio is the risk of heartworm disease in dogs. I wish I had seen this post first. Simparica Trio contains three active ingredients . just gave my one year old dauchund her first dose of simparica My vet didnt tell me, We gave our Yorkie this and she went into seizures later in the daywhat if any thing can be done. The day I gave it to him, he was up all night just randomly crying and yelping like he was in pain. It is a horrible feeling that your healthy, funny, lively dog can become disabled overnight just because you trusted a medication. Product Overview. It started working on him right away, Diarrhea. I wish every one the best. 3 months ago he began having seizures, he had one every day for a week. However, your dog must have a history of negative test results for these diseases. He is disoriented, his head just hangs and he is lifeless. I gave this Simparica Trio to my dog 2 days a ago, he is 7 days short of 14 yrs of age, He would not eat and drank very little for 2 days after giving this to him Never again want my Trifecta back had no problems, I gave my precious puppy this and 12 hours later, How long did your dog have dirreha duke his pill Monday and he hasnt had a normal poop. The only thing the vet told me was that his ATL liver enzyme levels were just slightly high (170) and it wasn't a concern and we could just do another blood test at his next check-up. this link is to an external site that may or may not meet accessibility guidelines. The vet does not feel it is due to Simparica but i think it could be. The company's thinking must be the profits outweigh the loses from any lawsuits lost its important to note that the law treats animals as property and the fix value of a dog is quite small and limited. She wanted me to monitor him carefully and wait to see how he did on his next dose of Simparica before continuing to prescribe it. She had some good days and we were hopeful but ultimately, she steadily declined. Since then I've researched loads and as you say the FDA put out a report. His first was a week after taking his simparica. Dogs with existing heartworm infections should be treated to remove the adult heartworms before going back on this medication. His vet doesn't think it has anything to do with the Trifexis but I cannot help but think it IS because he was just fine the day before I gave it to him! There was no clear diagnosis but it was clearly neurological. Not even going to risk it . It comes as the first choice when prescribing a treatment due to its liver flavor. It is important to work with your veterinarian to ensure the best flea/tick and heartworm prevention plan for your pets specific needs. I must admit that I am pretty nervous about it, but we shall see. Some years back my husband gave vet approved & sold oral flea/tic medication to each of our 2 Standard Poodles. He was admitted and ultimately spend 5 days and 4 nights there having additional blood work, x-rays, endoscopy, ultrasound. Our pups had been on next guard and heart guard with no issues but new vet stopped selling those products so switched to to the simparica trio - gave a dose to our 7 ur old 71 pound blue tick coonhound Frazier and our 10 mo 45 pound labradoodle- Watson. I have every intention of calling and filing a complaint. She hasn't had any of the diarrhea or eating issues, but has had one of her eyes that gets red and the inner eyelid partially covers her pupil. Poor baby has had vomiting and diarrhoea ever since. They both got similar issues and this was the only thing they both did. I finally got him to eat some chicken and he threw that up 2 hours later. For me, Simparica Trio has made parasite control effective and easyI just give her one chewable tablet each month. That was when I lived in Fort Lauderdale. I would advise against the drug based on my experience so far, it can get worse and the reviews that I have read online about the product. If your dog has reactions to this medicine, push fluids! The risk and consequences of tick paralysis are much higher than the risk of side effects. I am interested in the petition and the company's response. I say yes! Not grass grazing either. This medicine is making her shaky/tremor, anxious, and she is panting a ton. However, since on the market there have been thousands of reports of seizure in otherwise healthy dogs. For the next 3-4 days I noticed he would be a bit hesitant to jump or hop around and play as he normally does (and his appetite was lower than usual). He had his second dose on 3rd July. Good luck. So scary. 4.3 4.3 out of 5 stars (34,534) $39.98 $ 39. Related questions. I took him to the emergency hosp. This was days ago when I could still get food into him and the result. She nearly died. After doing more research on their monthly medication, I will no longer use Simparica Trio nor ever recommend it. Hes been on it for six months. I advise all pet owners to know the side effects. MONEY!!. How is ur puppy? I don't know if the lump came from it or something else. This medication works within the first few hours after administration to kill fleas present on your dog, and is dosed by weight, so it is important to use the correct-sized medication for your pet. My poor baby! Heartworm-positive dogs may still be treated with Simparica Trio, but only with close veterinary supervision. Can you tell me if your dog is back to normal now?!?! Poor dog prob thinks HE did something wrong. Gave Simparica to my dog yesterday. My dog is still having tremors 5 months after taking Simparica. Does any one think this could be a reaction to Simparico Trio? He ran bloods and sent her home with Keppra three times a day, after two weeks she is now down to twice a day. The prescription-only chewable tablet is given once a month to dogs and puppies eight weeks and older. The vet came and picked her up and cut her opened and said and told me she could anything wrong with her so it was either she was poisoned or it was a neurological disorder. I had to put him laundry room for the night (no Carpet). I honestly think she had a reaction to the medication. Shes not the carefree setter she was prior to this medication. He has no appetite, wont drink water and his mouth is so dry. They have increased and worsened over the last 3 months. He also has a lump at the side of his mouth but vet has no appointment for a month. Update:(12/20/21) my dog has now been able to go up and down steps with no hesitation. She has been itching uncontrollably since I gave her the simparica. well my lola went into labor xmas day. I am so sorry to all of you and my heart goes out to you and your babies. I took him to the energy vet in the morning, he couldnt find any cause for pain, only he yelped a bit on his neck, they had trouble getting him in, he was yanking his neck around as he is afraid of the vet since getting fixed. He had a serious skin issue a few months back and it was blamed on fleas. My dog is experiencing these same symptoms and had his first accident in yearsss in the house and is drinking water excessively. Needless to say, we will no longer be giving this to our lab or our other dog. We hope this will solve our problems and he can live a healthy and happy life. I just wanted to get another opinion before we move forward. Today he wont eat, is sleeping all day, and when he is up he is panting heavily. I just found these comments and I am feeling terrible. It seems to be clearing up with Rx eye drops. If anyone has suggestions or knows how else I can help my little guy please let me know. I only researched it after he started not feeling well, just trusted my vet that this was safe. The next day Bellas stools were quite soft but still had some structure. Use with caution in dogs with a history of seizures. Our baby isnt the same at all since his one and only dose of Simparica. He is just laying in his crate . We took him to vet and they gave nausea meds and kept him overnight. He took simparica trio 3 weeks ago and I cant wait until its out of his system! Side effects with Simparica are not common. Really angry this drug is on the market and pushed by many vets. Unfortunately, I didn't realize the tremors were possibly caused by the drug. At first B seemed fine. It went away, I thought the diarrhea was from some of the junk she eats off of the ground. Random vomitting is no fun either. But he still is suffering from lethargy, polyuria and polydispia basically still drinks and pees non stop. This was the 2nd does I have him. Last year I gave them this but didn't notice any issues. Simparica, NexGard, Bravecto & Credelio may not increase the number of seizures, but the risk is real. This simple-to-give oral monthly treatment protects dogs against heartworm disease as well as against ticks and fleas and intestinal worms like roundworms and hookworms. Even with what she has been through we have to wait until Dec 1st to see the Neurologist as there is only one in the State of Maine. Our boy Axel had been on Heartgard his entire life. I gave my dog simparica trio. Any response from the company? We reported it with the company and they are reimbursing for vet bills, maybe you can report as well. I fed him a diet of boiled chicken and rice for 3 days and began to introduce his food which is a limited ingredient type. I am so incredibly upset with myself for trusting my vet and giving my dog this product. So new pup goes on garlic tabs-as he growing I'm upping the amount because I wanted him to be protected. He is pissing a lot and often and drinking a lot of water. Started in February and within a couple of weeks ears started twitching. If she recovers, cause is the Simparica. PROS Treats adult fleas and prevents flea and tick infestations Effective against five types of tick Liver flavored tablet FDA Approved CONS This excerpt is from the healthline website and in reference to humans "GABA is considered an inhibitory neurotransmitter because it blocks, or inhibits, certain brain signals and decreases activity in your nervous system. I dont want to have to put my dog down but hes suffering. He is still not himself, walks very slowly and is definitely not feeling his best. I never saw a flea because he has a very thick coat. I gave the 1st one to my dog, 1st of this month. I am so worried after reading these comments. Simparica and Simparica Trio are available by prescription only. It's definitely not! By the evening she lost the use of her hind legs. If anyone has discovered what can help please let me know. On August 17th, we had to rush him to the ER because he was not moving. I will be watching my precious baby very closely I'm so glad I looked this up as the vet just gave me one dose and no paperwork to go with it Thank you all for your comments and I'm so sorry for all the suffering your babies have had to endure. This went on for 4 hours. This stuff should be banned. I understand them charging for the Euthanasia and cremation but they said they would keep her for 12 hours and she was put down at around 3:00 which was 1/2 the time they agreed on.Now he will get none of the fees back that the company offered for the dogs care, and hey don't have their dog .On top of that they have 3,500.00 vet bills.Why are vets allowed to charge so much?it is more than a person.It really seems as though they don't care about the pets or the people that own them Also why is these types of flea meds still on the market and why is there no legal action available for the poor consumers.I feel like they were legally assaulted by all involved and let us not forget the poor 2 year old rescue dog who ended up having a terrible short life.How unfair. After spending the day at the ER Vet where they did bloodwork and several x-rays all coming back normal, they sent her home with Keppra. Then I saw this and realized. Why the vets use this treatment after so many side effects being reported is disgusting. No more itching but covered in same scabs. I called my Vet and waited all day for them to call back, useless. Im certain that its the simparica. I hope it is better. Was checking out before using . Argh. Kind of ooze. By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. Went to a different vet, within minutes he found a large mass on my Poms abdomen. Seems like it was directly related to the medication. Simparica, Nexgard, Bravecto and Credelio are part of a group called Isoxazoline drugs. I came across this site and read so much about symptoms that I now realize he has been having. I am up writing this 4 a.m. since our Lambchop is too restless to sleep! I am hoping it is almost all out of her system. What kind of supplements are you giving her? I brought him to the vet and they keep trying to say excessive water drinking isnt a side effect but its the only thing that is different that Ive given my pup. Im so angry at these drug companies and vets for selling this crap. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions . I did not notice any side effects. I had placed an order with Pet Meds for the prescription before I saw any of these side effects.I will be returning this medication and order Heartgard and not sure what we will do for flea and ticks, since he turns his nos Simparica Trio, e to the Nexgard and we really dont feel safe with our Grandson around the topical or collarAny suggestions? Heres what you need to know about why cats purr and what your cat may be telling you when her motor is running. I'm so scared. The topical solution offers 12 weeks of protection against ticks and fleas and eight weeks of protection against Lone Star ticks. I gave 2 of my older Labs a dose of Simparica on a Saturday. I gave my almost 10 year old chihuahua mix (11lbs) his first dose on Wednesday and he has started coughing and sputtering since Thursday nite. My 3 other poodles unaffected. In general dogs tolerate very well sarolaner at the therapeutic dose range (2 to 4 mg/kg). He wouldnt survive surgical attempt to go in and try to figure out what was going on. Simparica Trio Recall can be trusted with their product. So sorry you are having to go through this! Considerations Just like any other medication, Simparica has the potential to interact with other drugs your dog is taking. Hi there, my dog has been taking simparica trio for two months. Youre an idiot then! This is apparently not true and that's why the article never goes on to explain exactly why it only works on GABA receptors in fleas and ticks yet not affect the GABA receptors in your dog. Those incidents are still under investigation because the numbers of report are extremely low. This is because drugs in the isoxazoline class have been associated with neurologic reactions including seizures, tremors, and ataxia in dogs with or without a history of neurologic disorders. Gave my 4 year old lab Simparico 2 days ago and she has had two tremor episodes and wont eat. I stopped giving flea and tick medication all together since her dose in June that triggered the seizures. All said, we are over $8K into vet bills and growing, Given that he had no noted medical issues prior, his vet and the urgent care vet both feel is was likely the Simparico. 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